Home - Translational Andrology and Urology

Focused Issue on Muscle-invasive Bladder Cancer

This focused issue on “Muscle-invasive Bladder Cancer” is edited by Dr. Ja Hyeon Ku, from Department of Urology, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, Korea; Dr. Ho Kyung Seo, from Center for Prostate Cancer, National Cancer Center, Goyang, Gyeonggi, Korea; and Dr. Seok Ho Kang, from Department of Urology, Korea University College of Medicine, Seoul, Korea.

Focused Issue on Urologic Management of the Transgender Patient

This focused issue on “Urologic Management of the Transgender Patient” is edited by Dr. Joseph J. Pariser and Dr. Sean P. Elliott from Department of Urology, University of Minnesota, Minneapolis, MN, USA; and Dr. Lee C. Zhao from Department of Urology, New York University Langone Health, New York, NY, USA.

Translational Andrology and Urology received its first Impact Factor: 2.113

We are pleased to announce that Translational Andrology and Urology(TAU) has received its first impact factor of 2.113 for the year 2018. Here, we would like to extend our heartfelt gratitude to all our editorial board members, guest editors, authors, and reviewers for their significant contributions. We look forward to the continuous cooperation with all the above mentioned and those who are interested in translational andrology and urology research to bring more exciting content to readers in the coming future.

Focused Issue on Surgery for Urologic Cancers

This focused issue on “Surgery for Urologic Cancers” is edited by Dr. Shomik Sengupta, Eastern Health Clinical School, Monash University, Melbourne, VIC, Australia.

Focused Issue on Kidney Disease

I find it difficult to separate kidney disease from urology. It seems to me that urology, as a branch of medicine that specializes in diseases of the male and female urinary tract system and the male reproductive system, and nephrology, specializing in the study of kidney disease and preservation of kidney health, should have closer links. I hope this special edition strengthens links with urology (in this special edition, with kidney cancer) and reminds readers of the importance of basic translational research in nephrology, urology, and outcomes of surgical intervention.

Focused Issue on Genetic Causes and Management of Male Infertility

This focused issue on “Genetic Causes and Management of Male Infertility” is edited by Dr. Keith Jarvi, from Division of Urology, Department of Surgery, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada; and Dr. Jared Bieniek, from Tallwood Urology & Kidney Institute, Hartford HealthCare, Farmington, CT, USA.

Focused Issue on Upper-Tract Urothelial Carcinoma: Current State and Future Directions

This focused issue on “Upper-Tract Urothelial Carcinoma: Current State and Future Directions” is edited by Dr. Jay D. Raman, Dr. Matthew G. Kaag and Dr. John Knoedler, from Division of Urology, The Penn State Hershey Medical Center, Hershey, Pennsylvania, USA

Focused Issue on Renal Transplantation in Urology

We begin with a review of immunosuppressive drugs used in non-transplant applications of Urology. There is good evidence for many of these indications, yet Urologists who aren’t involved with transplantation are often hesitant to use them. Transplant specific reviews include use of machine preservation and perfusion of kidneys and ABO incompatible protocols. Broader topics include specific urologic issues in pediatric transplantation, management of post-operative urologic complications and challenges in HIV positive transplant patients. Finally we cover post-operative medical complications including erectile dysfunction, neurologic complications and male infertility.

Focused Issue on Management of Non-muscle Invasive Bladder Cancer

Our goal was to put together an UpToDate guide for all urologists and researchers pursuing the improvement of their knowledge on non-muscle invasive bladder cancer. As guest editors of the present issue of TAU, we tried to provide insight on all aspects concerning non-muscle invasive bladder cancer starting from its epidemiology, passing through the description of new technical aspects of transurethral resection, leading to postoperative management including the identification of candidates for radical surgery or intravesical instillation therapy

Focused Issue on Current Topics of Reconstructive Urologic Surgery

This focused issue on “Current Topics of Reconstructive Urologic Surgery” is edited by Dr. Allen Morey, from Department of Urology, Texas Southwestern Medical Center, Dallas, TX, USA; and Dr. Boyd Viers, from Department of Urology, Mayo Clinic, Rochester, MN, USA.

Focused Issue on Testicular Cancer

This focused issue on “Testicular Cancer” is edited by Dr. Wade Sexton and Dr. Scott Gilbert, from Department of Genitourinary Oncology, Moffitt Cancer Center, Tampa, FL, USA.

Focused Issue on Minimally Invasive Treatments for Kidney Stones

This focused issue on “Minimally Invasive Treatments for Kidney Stones” is edited by Dr. Bhaskar Somani, Department of Urology, University Hospital Southampton NHS Trust, Southampton, Hampshire, UK.

Focused Issue: Detection of Lymph Node Metastases in Genitourinary Cancers edited by Dr. Baris Turkbey

This issue of Translational Andrology and Urology (TAU) is devoted to “Detection of Lymph Node Metastases in Genitourinary Cancers”, which is an evolving topic due to continuous high-level research in the field specifically in imaging and imaging guided surgery/intervention. In this issue, many experts shared their clinical and research experiences through high quality review articles on a diverse group of genitourinary cancers and they present a wide variety of lymph node detection techniques including conventional imaging, sentinel node imaging, novel positron emission tomography and magnetic resonance imaging. As the guest editor of TAU, I aimed to include the most up-to date information on the topic.

Focused Issue on Contemporary Issues and Controversies in Men’s Health

This focused issue on “Contemporary Issues and Controversies in Men’s Health” is edited by Dr. Larry I. Lipshultz, from Scott Department of Urology, Center for Reproductive Medicine, Baylor College of Medicine, Houston, TX, USA; and Dr. Alexander W. Pastuszak, from Department of Surgery-Urology, University of Utah School of Medicine, Salt Lake City, UT, USA.

Translational Andrology and Urology is indexed in SCIE: A milestone for the development of TAU

On December 12, 2018, we received the good news from Clarivate Analytics (former Thomson Reuters Intellectual Property and Science Business) that Translational Andrology and Urology (TAU) has been indexed in Science Citation Index Expanded (SCIE) and articles published since 2016 will all be included.

Welcome to the Visualized Minimally Invasive Urological Surgery Column, a section featured by high-quality surgical videos!

With the rapid development in the science technology as well as advancement in surgical technique, there’s an increasing attention to and demand of Visualized Surgery from our readers for in-depth and practical minimally invasive surgical technique learning. To fit for this trend, and more importantly, for the instructional and educational purpose of learning and improving surgical technique and skill for all urological surgeons around the world, the Translational Andrology and Urology.

TAU Annual Report (2018)

We are glad to present the 2018 Annual Report of TAU here. There were 237 articles published in TAU. The total citation of TAU has increased from 971 to 2186 in the past 2018 and the total retrieval of the journal in PubMed has also increased significantly. In Dec. 2018, TAU was indexed by SCIE, which was a big step for us. More information is shown in the Annual Report.

Focused Issue on Controversies in Minimally Invasive Urologic Oncology

This focused issue on “Controversies in Minimally Invasive Urologic Oncology” is edited by Dr. Marc C. Smaldone, from Division of Urologic Oncology, Department of Surgical Oncology, Fox Chase Cancer Center, Temple University Health System, Philadelphia, PA, USA; and Dr. Jeffrey J. Tomaszewski, Division of Urology, Department of Surgery, MD Anderson Cancer Center at Cooper, Cooper Medical School of Rowan University, Camden, NJ, USA

Focused Issue: Personalized Prostate Cancer Care edited by Drs. Soroush Rais-Bahrami and Jennifer B. Gordetsky

Across the field of oncology, but particularly in relation to prostate cancer, the treatment landscape has shifted toward personalized medicine in the era of improved imaging, molecular techniques, and genomics. These advances have in turn allowed for more individualized characterization of cancer processes and improved risk stratification. A personalized approach to cancer detection and characterization enables us to provide our patients with optimal treatments and improved clinical outcomes. As guest editors of this issue of Translational Andrology and Urology (TAU), we set forth to present a variety of poignant topics addressing the personalized approach to prostate cancer detection, risk stratification, and management. Herein, we present investigations that are on the frontier of prostate cancer care, realms where we expect further research growth and development in the coming years.

Focused Issue: Male Genitourinary Reconstruction and Trauma edited by Drs. Benjamin N. Breyer and E. Charles Osterberg

This issue brings together the research and evidence-based practices of many experts in our field. These experts are thought-leaders and have contributed to advancing male GU reconstruction and trauma in a multitude of ways. We are extremely grateful for all the authors’ hard work and contribution to make this a unique and exciting issue in TAU.

Focused Issue: Knowledge Gaps in Male Infertility edited by Drs. James M. Hotaling and Ranjith Ramasamy

The objective of this issue of Knowledge Gaps in Male Infertility is to highlight the several advances that have happened in the care of infertile men. Our goal in writing this is to identify what research is needed to move the field forward and, ultimately, imagine what issues need to be solved in order to bring male infertility care to the same level of diagnosis and treatment as female infertility. Our hope is that by identifying what the roadblocks are we can stimulate others to pursue the key areas in our field that are holding us back. This issue should stimulate others to look for funding opportunities and industry partnerships that can move us beyond these roadblocks.

Focused Issue: Radiation Therapy for Prostate Cancer edited by Dr. Mark K. Buyyounouski

The intended purpose of this issue is to raise awareness of radiation therapy and to provide current perspectives on some of its most important topics related to prostate cancer. Whether you are the most seasoned senior clinician or junior trainee, this issue is a resource for reviewing the literature, formulating practice patterns and educating patients. And, translational scientists and clinical researchers who are considering the future of prostate radiation therapy have a concise collective of ideas and opinion from well-recognized and leading experts in the field.

Focused Issue: Active Surveillance for Prostate Cancer edited by Drs. Marc A. Dall’Era, Benjamin J. Davies, Scott Eggener

Prostate cancer management continues to rapidly evolve for men presenting with all stages of disease. In response to the pandemic of over detection and overtreatment of indolent prostate cancer, active surveillance has become a standard management strategy for many men with low-risk cancers. Many challenges with clinical implementation of active surveillance persist, including optimal selection criteria, surveillance strategies, indicators of disease progression and when further treatment may be warranted.

Focused Issue: Prostate Cancer Screening and Active Surveillance in the Western World edited by Dr. Monique J. Roobol

Prostate cancer screening and active surveillance are two topics within the field of prostate cancer research that have evolved from virtually non-existing in the 70s of the last century to now being in the centre of research. While it has been shown that PSA based screening can save lives, it is clear that a screening algorithm on the basis of PSA and random systematic prostate biopsy is not the way to go. It leads to unacceptable rates of unnecessary (repeat) testing and, in addition, leads to thousands of men diagnosed with low-risk prostate cancer that often get risky treatment they don’t need.

Focused Issue: Bladder Cancer: Genetics and Biomarker for Optimized Clinical Decision-making and Improved Outcomes by Dr. Michael Rink

This special issue of Translational Andrology and Urology (TAU), therefore, is focused on “genetics and biomarker in bladder cancer for optimized clinical decision-making and improved outcomes”. As editor, I strove to present a current, state-of-the-art and global perspective of the genetically heterogeneity in UCB as well as different approaches, possibilities and implications of biomarkers in UCB for current and future clinical decision-making, management and research. Established national and international experts as well as rising stars were invited to contribute to this comprising and timely subject of major importance for our daily practice and future clinical trial design.

Focused Issue: Penile Prosthesis and Penile Implants by Dr. Jason R. Kovac

This special edition of Translational Andrology and Urology has been developed with the primary goal of establishing a wide-ranging primer for surgeons who are currently implanting penile prosthetics as well as students and physicians who are looking to get more reliable information and background into current topics.

Focused Issue: Management of Penile Cancer

Penile cancer remains a relatively infrequent malignancy in North America, Europe, and Asia nevertheless it is a devastating disease which portends an adverse prognosis in those presenting with advanced disease. Similarly, the clinical and surgical care remains highly diverse across many parts of the world often applying non-evidence based approaches in their management.

Focused Issue: Sperm DNA Fragmentation by Drs. Ashok Agarwal, Ahmad Majzoub, Sandro C. Esteves and Chak-Lam Cho

Sperm DNA fragmentation (SDF) has been generally acknowledged as a valuable tool for male fertility evaluation. While its detrimental implications on sperm function were extensively investigated, little is known about the actual indications for performing SDF analysis. SDF testing is recommended in patients with clinical varicocele and borderline to normal semen parameters as it can better select varicocelectomy candidates. High SDF is also linked with recurrent spontaneous abortion (RSA) and can influence outcomes of different assisted reproductive techniques.

Focused Issue: Technique and Complications from the Masters in Andrologic Surgery edited by Dr. Tobias S Kohler

“Good decisions come from experience, and experience comes from bad decisions”—author unknown. Each article in this special edition features a step-by-step technique description of a surgery in andrology along with the little details and nuances the authors have learned from myriad repetition. Not only will the reader learn from these techniques, but they will learn from a detailed description (or potential avoidance) of the authors’ little or big complications which helped orchestrate their operative flow into its current symphonic form.

Focused Issue: Functional Urology by Dr. Johan Gani and Helen E. O’Connell

We are pleased to introduce this special edition of Translational Andrology and Urology (TAU), with a focus on contemporary topics in Functional Urology. Local (Australia and New Zealand) and international experts have contributed to this issue and we have included original studies as well as comprehensive review papers.

Focused Issue: Magnetic Resonance Imaging in Prostate Cancer by Drs. Marc A. Bjurlin, Andrew B. Rosenkrantz, Herbert Lepor and Samir S. Taneja

MRI offers increasingly reliable visualization of potentially significant prostate cancers, thereby guiding biopsy to allow better sensitivity and negative predictive value. In applying MRI-targeted biopsy, we have learned the significance of MRI findings and evolved pre-biopsy MRI to serve as a means by which to better select patients for biopsy and identify lesions for biopsy. Rather than diagnosing all cancers of the prostate, we have now begun the shift the paradigm to selective identification of only those cancers that may cause harm.

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Vol 8, No 4 (August, 2019)

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eBooks

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Editorial Commentary

Prostate specific membrane antigen (PSMA) imaging: the past is prologue

Peter L. Choyke, Kirsten Bouchelouche

PDF Pages: 283-285 Full Text

Urinary tract infections in patients undergoing radical cystectomy and urinary diversion: challenges and considerations in antibiotic prophylaxis

Evangelos N. Symeonidis, Matthew E. Falagas, Fotios Dimitriadis

PDF Pages: 286-289 Full Text

What are roles of multiparametric magnetic resonance imaging prior to transurethral resection of bladder tumor?

Fumitaka Koga

PDF Pages: 290-291 Full Text

Original Article

Complications and clinical management of ultrasound-guided renal allograft biopsies

Jiali Fang, Guanghui Li, Lu Xu, Lei Zhang, Wei Yin, Xingqiang Lai, Yuhe Guo, Rongxin Chen, Li Li, Yunyi Xiong, Luhao Liu, Tao Zhang, Jiao Wan, Peng Zhang, Hailin Xu, Jialin Wu, Guanghui Pan, Junjie Ma, Zheng Chen

PDF Pages: 292-296 Full Text

High grade renal trauma management: a survey of practice patterns and the perceived need for a prospective management trial

Rachel A. Moses, Ross E. Anderson, Sorena Keihani, James M. Hotaling, Raminder Nirula, Daniel J. Vargo, Jeremy B. Myers

PDF Pages: 297-306 Full Text

Efficacy and safety of novel low-intensity pulsed ultrasound (LIPUS) in treating mild to moderate erectile dysfunction: a multicenter, randomized, double-blind, sham-controlled clinical study

Wanshou Cui, Huixi Li, Ruili Guan, Meng Li, Bicheng Yang, Zhanwei Xu, Maofan Lin, Long Tian, Xiaodong Zhang, Bao Li, Weiguang Liu, Zhilong Dong, Zhiping Wang, Tao Zheng, Weixing Zhang, Guiting Lin, Yinglu Guo, Zhongcheng Xin

PDF Pages: 307-319 Full Text

Lower urinary tract symptoms (LUTS) before and after robotic-assisted laparoscopic prostatectomy: does improvement of LUTS mitigate worsened incontinence after robotic prostatectomy?

Lukas Dommer, Jan A. Birzele, Khosrow Ahmadi, Mario Rampa, Daniel J. Stekhoven, Räto T. Strebel

PDF Pages: 320-328 Full Text

Tamsulosin dispensation patterns in the United States: a real-world, longitudinal, population claims database analysis

Bruce R. Kava, Anna E. Verbeek, Jan M. Wruck, Marc Gittelman

PDF Pages: 329-338 Full Text

A new strategy for the treatment of sorafenib-refractory metastatic renal cell carcinoma in China: combination with intermittent chemotherapy

Zicheng Xu, Xiao Li, Feng Qi, Xin Hu, Yuxiao Zheng, Hongzhou Cai, Ting Xu, Bin Yu, Qing Zou

PDF Pages: 339-345 Full Text

Cut-off values of the Johnsen score and Copenhagen index as histopathological prognostic factors for postoperative semen quality in selected infertile patients undergoing microsurgical correction of bilateral subclinical varicocele

Thiago Afonso Teixeira, Juliana Risso Pariz, Robertson Torres Dutra, Paulo Hilario Saldiva, Elaine Costa, Jorge Hallak

PDF Pages: 346-355 Full Text

The effect of sperm DNA fragmentation index on assisted reproductive technology outcomes and its relationship with semen parameters and lifestyle

Hongyi Yang, Gang Li, Haixia Jin, Yihong Guo, Yingpu Sun

PDF Pages: 356-365 Full Text

Comparison and outcomes of nonobstructive azoospermia patients with different etiology undergoing MicroTESE and ICSI treatments

Xiangfeng Chen, Yi Ma, Shasha Zou, Siqi Wang, Jin Qiu, Qian Xiao, Liang Zhou, Ping Ping

PDF Pages: 366-373 Full Text

Fournier’s gangrene: a modern analysis of predictors of outcomes

Jeffrey D. Sparenborg, Jacob A. Brems, Andrew M. Wood, Jonathan J. Hwang, Krishnan Venkatesan

PDF Pages: 374-378 Full Text

Knowledge of front-line health workers on the role of urethral catheterization for primary prevention of obstetric fistula in Ibadan, Nigeria

Oluwasomodoyin Olukemi Bello, Imran Oludare Morhason-Bello, Olatunji O. Lawal, Rukayat Adeola Abdussalam, Oladosu Akanbi Ojengbede

PDF Pages: 379-386 Full Text

Erectile dysfunction management after failed phosphodiesterase-5-inhibitor trial: a cost-effectiveness analysis

Rachel A. Moses, Ross E. Anderson, Jaewhan Kim, Sorena Keihani, James R. Craig, Jeremy B. Myers, Sara M. Lenherr, William O. Brant, James M. Hotaling

PDF Pages: 387-394 Full Text

Review Article

Effect of whole-body vibration exercise in the pelvic floor muscles of healthy and unhealthy individuals: a narrative review

Eliane de Oliveira Guedes-Aguiar, Danúbia da Cunha de Sá-Caputo, Eloá Moreira-Marconi, Silvana Maria de Macêdo Uchôa, Patrícia Zaidan de Barros, Ericka Kirsthine Valentin, Anke Bergmann, Redha Taiar, Mario Bernardo-Filho

PDF Pages: 395-404 Full Text

Case Report

Sertoli cell only syndrome induced by a varicocele

Parviz K. Kavoussi, Caitlin Hunn, Melissa S. Gilkey, Shu-Hung Chen, Keikhosrow M. Kavoussi, J. David Wininger, Shahryar K. Kavoussi

PDF Pages: 405-408 Full Text

Review Article

Strategies for maintaining penile size following penile implant

King Chien Joe Lee, Gerald B. Brock

Phalloplasty for the genetic male

Giulio Garaffa, Gabriele Antonini, Vincenzo Gentile, David J. Ralph

Exogenous testosterone: a preventable cause of male infertility

Lindsey E. Crosnoe, Ethan Grober, Dana Ohl, Edward D. Kim

Premature ejaculation: do we have effective therapy?

Ege Can Serefoglu, Theodore R. Saitz, Landon Trost, Wayne J.G. Hellstrom

Peyronie’s disease: current therapy

Clay M. Pendleton, Run Wang

Expert Opinions on Challenging Cases

Commentary on the myths of Peyronie’s disease

Alex K Wu, Tom F Lue

Commentary

Randall plaque versus renal stone?

Thomas Chi, Joe Miller, Marshall L. Stoller

Original Article

Surgical treatment of Peyronie’s disease by modified 16-dot placation in China

Wen Ji Li, Haijun Yao, Ke Zhang, Zhikang Cai, Jun Da, Mingxi Xu, Zhong Wang

Does normalizing PSA after successful treatment of chronic prostatitis with high PSA value exclude prostatic biopsy?

Sherif Azab, Ayman Osama, Mona Rafaat

Podium Lecture

PL 03. Male sexual function before and after urethral stricture surgery

Hong Li

Review Article

Mechanisms of resistance in castration-resistant prostate cancer (CRPC)

Thenappan Chandrasekar, Joy C. Yang, Allen C. Gao, Christopher P. Evans

Inflammation in prostate cancer progression and therapeutic targeting

Timothy Stark, Lydia Livas, Natasha Kyprianou

The current and future role of magnetic resonance imaging in prostate cancer detection and management

Jan Philipp Radtke, Dogu Teber, Markus Hohenfellner, Boris A. Hadaschik

Pelvic radiotherapy and sexual function in women

Pernille Tine Jensen, Ligita Paskeviciute Froeding

Active surveillance and focal therapy for low-intermediate risk prostate cancer

Laurence Klotz

Future perspectives of prostate cancer therapy

Murali Gururajan, Edwin M. Posadas, Leland W. K. Chung

Upper urinary tract disease: what we know today and unmet needs

Romain Mathieu, Karim Bensalah, Ilaria Lucca, Aurélie Mbeutcha, Morgan Rouprêt, Shahrokh F. Shariat

Original Article

Overall satisfaction, sexual function, and the durability of neophallus dimensions following staged female to male genital gender confirming surgery: the Institute of Urology, London U.K. experience

Maurice M. Garcia, Nim A. Christopher, Francesco De Luca, Marco Spilotros, David J. Ralph

The efficacy of resiniferatoxin in prevention of catheter related bladder discomfort in patients after TURP - A pilot, randomized, open study

Ning Zhang, Peng Zhang, Xiaodong Zhang, Yong Yang

Review Articles

Decoding the androgen receptor splice variants

Changxue Lu, Jun Luo

Epithelial mesenchymal transition (EMT) in prostate growth and tumor progression

Campbell M. Grant, Natasha Kyprianou

Steroid hormone synthetic pathways in prostate cancer

Elahe A. Mostaghel

Androgen receptor gene mutation, rearrangement, polymorphism

Kurtis Eisermann, Dan Wang, Yifeng Jing, Laura E. Pascal, Zhou Wang

Androgen receptor-mediated non-genomic regulation of prostate cancer cell proliferation

Ross S. Liao, Shihong Ma, Lu Miao, Rui Li, Yi Yin, Ganesh V. Raj

Androgen receptor genomic regulation

Hong-Jian Jin, Jung Kim, Jindan Yu

Near-infrared fluorescence and nuclear imaging and targeting of prostate cancer

Jason Wu, Dongfeng Pan, Leland W.K. Chung

Current clinical challenges in prostate cancer

Jonathan L. Silberstein, Sumanta Kumar Pal, Brian Lewis, Oliver Sartor

Mini-Review

Epidemiology of urethral strictures

Amjad Alwaal, Sarah D. Blaschko, Jack W. McAninch, Benjamin N. Breyer

Review Article

Reactive oxygen species, inflammation and calcium oxalate nephrolithiasis

Saeed R. Khan

Guideline

Clinical utility of sperm DNA fragmentation testing: practice recommendations based on clinical scenarios

Ashok Agarwal, Ahmad Majzoub, Sandro C. Esteves, Edmund Ko, Ranjith Ramasamy, Armand Zini

Review Article

Future perspectives of prostate cancer therapy

Murali Gururajan, Edwin M. Posadas, Leland W. K. Chung

Small RNA and its application in andrology and urology

Ji Wang, Long-Cheng Li

TGF-β mediated DNA methylation in prostate cancer

Chung Lee, Qiang Zhang, Xaolin Zi, Atreya Dash, Marcelo B Soares, Farahnaz Rahmatpanah, Zhenyu Jia, Michael McClelland, Dan Mercola

Cystine nephrolithiasis

Hasan Fattah, Yasmin Hambaroush, David S. Goldfarb

Outlining the limits of partial nephrectomy

Sameer Chopra, Raj Satkunasivam, Chandan Kundavaram, Gangning Liang, Inderbir S. Gill

Mechanisms of resistance in castration-resistant prostate cancer (CRPC)

Thenappan Chandrasekar, Joy C. Yang, Allen C. Gao, Christopher P. Evans

Prostate cancer metastasis: roles of recruitment and reprogramming, cell signal network and three-dimensional growth characteristics

Shabnam Ziaee, Gina Chia-Yi Chu, Jen-Ming Huang, Shirly Sieh, Leland W. K. Chung

Inflammation in prostate cancer progression and therapeutic targeting

Timothy Stark, Lydia Livas, Natasha Kyprianou

Sympathetic nervous system and chronic bladder pain: a new tune for an old song

Ana Charrua, Rui Pinto, Lori Ann Birder, Francisco Cruz

Angiogenic factors, bladder neuroplasticity and interstitial cystitis—new pathobiological insights

Ricardo Saban

Increased bladder permeability in interstitial cystitis/painful bladder syndrome

Robert E. Hurst, Beverley Greenwood-Van Meerveld, Amy B. Wisniewski, Samuel VanGordon, Hsueh Kung Lin, Bradley P. Kropp, Rheal A. Towner

Magnetic resonance imaging (MRI)-based radiomics for prostate cancer radiotherapy

Fei Yang, John C. Ford, Nesrin Dogan, Kyle R. Padgett, Adrian L. Breto, Matthew C. Abramowitz, Alan Dal Pra, Alan Pollack, Radka Stoyanova

Editorial

PIVOT and the challenges of localized prostate cancer care

Aviva E. Weinberg, James D. Brooks

Original Article

Overall satisfaction, sexual function, and the durability of neophallus dimensions following staged female to male genital gender confirming surgery: the Institute of Urology, London U.K. experience

Maurice M. Garcia, Nim A. Christopher, Francesco De Luca, Marco Spilotros, David J. Ralph

Incidence of urinary extravasation and rate of ureteral stenting after high-grade renal trauma in adults: a meta-analysis

Sorena Keihani, Ross E. Anderson, Michelle Fiander, Mary M. McFarland, Gregory J. Stoddard, James M. Hotaling, Jeremy B. Myers

Safety and efficacy of daily Revactin^® in men with erectile dysfunction: a 3-month pilot study

Sabine Nguyen, Jacob Rajfer, Magda Shaheen

Research Highlights

Enzalutamide: the emperor of all anti-androgens

Emmanuel S. Antonarakis

Review Articles

Androgen receptor gene mutation, rearrangement, polymorphism

Kurtis Eisermann, Dan Wang, Yifeng Jing, Laura E. Pascal, Zhou Wang

Androgen receptor epigenetics

Changmeng Cai, Xin Yuan, Steven P. Balk

Androgen receptor genomic regulation

Hong-Jian Jin, Jung Kim, Jindan Yu

Decoding the androgen receptor splice variants

Changxue Lu, Jun Luo

Epithelial mesenchymal transition (EMT) in prostate growth and tumor progression

Campbell M. Grant, Natasha Kyprianou

Steroid hormone synthetic pathways in prostate cancer

Elahe A. Mostaghel

Near-infrared fluorescence and nuclear imaging and targeting of prostate cancer

Jason Wu, Dongfeng Pan, Leland W.K. Chung

Mini-Review

Multi-peptide immunotherapeutic vaccine for renal cell carcinoma: getting the troops all worked up

Kavitha Yaddanapudi, John W. Eaton

Review Article

Kidney stone risk following Roux-en-Y gastric bypass surgery

Benjamin K. Canales, Ricardo D. Gonzalez

Review Article

Reactive oxygen species, inflammation and calcium oxalate nephrolithiasis

Saeed R. Khan

Review Article: Hypospadias

Do endocrine disruptors cause hypospadias?

Sisir Botta, Gerald R. Cunha, Laurence S. Baskin

Below are the latest Translational Andrology and Urology articles published online ahead of print publication.

Editorial

Challenges of urine-based molecular assays for the detection of urothelial cancer

Joep J. de Jong, Kim E. M. van Kessel, Monique J. Roobol, Joost L. Boormans

Perspective

The future of penile prostheses for the treatment of erectile dysfunction

John P. Lindsey II, Tom F. Lue, Alan W. Shindel

Review Article

The evolving role of lymphadenectomy for bladder cancer: why, when, and how

Vignesh T. Packiam, Matvey Tsivian, Stephen A. Boorjian

Current management and management controversies in early- and intermediate-stage of nonseminoma germ cell tumors

Salim K. Cheriyan, Marilin Nicholson, Ahmet M. Aydin, Mounsif Azizi, Charles C. Peyton, Wade J. Sexton, Scott M. Gilbert

Robotic renal surgery for renal cell carcinoma with inferior vena cava thrombus

Selma Masic, Marc C. Smaldone

Defining risk of micrometastatic disease and tumor recurrence in patients with stage I testicular germ cell tumors

Ryan P. Werntz, Scott E. Eggener

The role of diagnostic imaging in the primary testicular cancer: initial staging, response assessment and surveillance

Kerry L. Thomas, Daniel Jeong, Jaime Montilla-Soler, Sebastian Feuerlein

A primer on extramammary Paget’s disease for the urologist

Joon Yau Leong, Paul H. Chung

Value of systematic sampling in an mp-MRI targeted prostate biopsy strategy

Martin J. Connor, Saiful Miah, Rajiv Jayadevan, Christopher C. Khoo, David Eldred-Evans, Taimur Shah, Hashim U. Ahmed, Leonard Marks

Testis-preserving strategies in testicular germ cell tumors and germ cell neoplasia in situ

Pia Paffenholz, David Pfister, Axel Heidenreich

Fertility considerations in men with testicular cancer

Neel V. Parekh, Scott D. Lundy, Sarah C. Vij

Prostate cancer biology & genomics

Hayley Whitaker, Joseph O. Tam, Martin J. Connor, Alistair Grey

Contemporary lymphatic interventions for post-operative lymphatic leaks

Bill S. Majdalany, Ghassan El-Haddad

Evolving therapies for Peyronie’s disease: how can we work towards new drugs?

Uros Milenkovic, Jolien Duponselle, Trinity J. Bivalacqua, Maarten Albersen

Minimally invasive therapies for Peyronie’s disease: the current state of the art

M. Ryan Farrell, Matthew J. Ziegelmann, Laurence A. Levine

A systematic review of salvage focal therapies for localised non-metastatic radiorecurrent prostate cancer

Christopher C. Khoo, Saiful Miah, Martin J. Connor, Joseph Tam, Mathias Winkler, Hashim U. Ahmed, Taimur T. Shah

Penile sparing therapy for penile cancer

Henry Han-I Yao, Shomik Sengupta, Justin Chee

Current and future trends in men’s health clinics

Justin J. Houman, Sriram V. Eleswarapu, Jesse N. Mills

The role of penectomy in penile cancer—evolving paradigms

Sarah O’Neill, Mitchell Barns, Filip Vujovic, Mikhail Lozinskiy

Inguinal lymph node dissection for penile cancer: a contemporary review

Jiasian Teh, Catriona Duncan, Liang Qu, Glen Guerra, Vignesh Narasimhan, Toan Pham, Nathan Lawrentschuk

Development of patient-derived xenograft models of prostate cancer for maintaining tumor heterogeneity

Changhong Shi, Xue Chen, Dengxu Ta

Towards a better testicular sperm extraction (TESE): novel sperm sorting technologies for non-motile sperm extracted by microdissection TESE

Cathy L. Mangum, Darshan P. Patel, Alexander R. Jafek, Raheel Samuel, Tim G. Jenkins, Kenneth I. Aston, Bruce K. Gale, James M. Hotaling

Open retropubic radical prostatectomy

Ryan Pereira, Andre Joshi, Matthew Roberts, John Yaxley, Ian Vela

Targeting the cancer lesion, not the whole prostate

Nishant Bedi, Deepika Reddy, Hashim U. Ahmed

Comprehensive men’s health and male infertility

Jeremy T. Choy, Michael L. Eisenberg

Surgical salvage in patients with advanced testicular cancer: indications, risks and outcomes

Ryan W. Speir, Clint Cary, Timothy A. Masterson

Techniques of robotic radical prostatectomy for the management of prostate cancer: which one, when and why

Shuo Liu, Ashok Hemal

Systemic therapy for primary and extragonadal germ cell tumors: prognosis and nuances of treatment

Bilal A. Siddiqui, Miao Zhang, Louis L. Pisters, Shi-Ming Tu

Therapeutic strategies for uncommon testis cancer histologies: teratoma with malignant transformation and malignant testicular sex cord stromal tumors

Mounsif Azizi, Ahmet M. Aydin, Salim K. Cheriyan, Charles C. Peyton, Matthew Montanarella, Scott M. Gilbert, Wade J. Sexton

Minimizing opioid consumption following robotic surgery

Ruchika Talwar, Shreyas S. Joshi

Commentary

Clinical utility of sperm DNA fragmentation testing: practice recommendations based on clinical scenarios

Murad M. Basar, Semra Kahraman

Original Article

Urethral atrophy is now a rare cause for artificial urinary sphincter revision surgery in the contemporary 3.5 cm cuff era

Rachel L. Bergeson, Yooni A. Yi, Ryan C. Baker, Ellen E. Ward, Michael T. Davenport, Allen F. Morey

Dutasteride in the long-term management of stuttering priapism

Ryan C. Baker, Rachel L. Bergeson, Yooni A. Yi, Ellen E. Ward, Allen F. Morey

Preventing the need for revision surgery after penile plication reconstruction of Peyronie’s deformities

Rohit S. Reddy, Yooni A. Yi, Jorge Fuentes, Rachel L. Bergeson, Michael T. Davenport, Allen F. Morey

Long-term device survival and quality of life outcomes following artificial urinary sphincter placement

Timothy C. Boswell, Daniel S. Elliott, Laureano J. Rangel, Brian J. Linder

An update on oxidized regenerated cellulose (fibrillar™) in reducing postoperative corporal bleeding following inflatable penile prosthesis surgery

Avery R. Wolfe, Michael T. Davenport, Alexander T. Rozanski, Nabeel A. Shakir, Ellen E. Ward, Mary L. West, Allen F. Morey

Balloon dilation performs poorly as a salvage management strategy for recurrent bulbar urethral strictures following failed urethroplasty

Yooni A. Yi, Alexander T. Rozanski, Nabeel A. Shakir, Boyd R. Viers, Ellen E. Ward, Rachel L. Bergeson, Allen F. Morey

The value of cystatin C and urinary and serum neutrophil gelatinase-associated lipocalin during the perioperative period of renal transplantation

Feng Li, Linkun Hu, Xiaojun Zhao, Wenqing Ge, Hao Pan, Wei Zhang, Yufeng Jiang, Xu Xu, Jianquan Hou, Jinxian Pu

The comparison of transurethral versus suprapubic catheter after robot-assisted radical prostatectomy: a systematic review and meta-analysis

Ze’an Li, Kaiwen Li, Wanhua Wu, Qiong Wang, Xiaoming Ma, Chunhao Lin, Shengmeng Peng, Yiming Lai, Fen Wang, Hai Huang

Long-term sequelae of inflatable penile prosthesis: clinical characteristics of patients who develop distal cylinder tip extrusion

Jorge L. Fuentes, Yooni A. Yi, Michael T. Davenport, Rachel L. Bergeson, Ellen E. Ward, Allen F. Morey

An open-label, single-arm pilot study to evaluate the efficacy of daily low dose tadalafil on depression in patients with erectile dysfunction

Jin Bong Choi, Kang Jun Cho, Joon Chul Kim, Chi-Un Pae, Jun Sung Koh

Outpatient buccal mucosal graft urethroplasty outcomes are comparable to inpatient procedures

Maxim J. McKibben, Michael T. Davenport, Partho Mukherjee, Nabeel A. Shakir, Mary L. West, Joceline S. Fuchs, Ellen E. Ward, Rachel L. Bergeson, Jeremy M. Scott, Allen F. Morey

Enhanced ambulatory male urethral surgery: a pathway to successful outpatient urethroplasty

Kevin J. Hebert, Jason Joseph, Timothy Boswell, Jack Andrews, Douglas A. Husmann, Boyd R. Viers

Fate of residual ureteral stump in patients undergoing robot-assisted radical nephroureterectomy for high-risk upper tract urothelial carcinoma

Ram A. Pathak, Ashok K. Hemal

The impact of prior external beam radiation therapy on device outcomes following artificial urinary sphincter revision surgery

Madeleine Grace Manka, Brian J. Linder, Laureano J. Rangel, Daniel S. Elliott

Persistent, long-term risk for ureteroenteric anastomotic stricture formation: the case for long term follow-up

David Y. Yang, Stephen A. Boorjian, Mary Beth Westerman, Robert F. Tarrell, Prabin Thapa, Boyd R. Viers

Pelvic fracture urethral injuries associated with rectal injury: a review of acute and definitive urologic and bowel management with long term outcomes

Douglas A. Husmann, Brian D. Montgomery, Boyd R. Viers

Age ≤40 is an independent predictor of anastomotic urethroplasty and successful repair of bulbar urethral strictures

Michael T. Davenport, Jeffrey T. Wooliscroft, Maxim J. McKibben, Nabeel Shakir, Joceline S. Fuchs, Yooni A. Yi, Boyd R. Viers, Rachel L. Bergeson, Ellen E. Ward, Allen F. Morey

Microenergy acoustic pulses induced myogenesis of urethral striated muscle stem/progenitor cells

Kai Cui, Ning Kang, Lia Banie, Tie Zhou, Tianshu Liu, Bohan Wang, Yajun Ruan, Dongyi Peng, Hsun Shuan Wang, Tianyu Wang, Guifang Wang, Amanda B. Reed-Maldonado, Zhong Chen, Guiting Lin, Tom F. Lue

Does race impact functional outcomes in patients undergoing robotic partial nephrectomy?

Ugo G. Falagario, Alberto Martini, John Pfail, Patrick-Julien Treacy, Kennedy E. Okhawere, Bheesham D. Dayal, John P. Sfakianos, Ronney Abaza, Daniel D. Eun, Akshay Bhandari, James R. Porter, Ashok K. Hemal, Ketan K. Badani

Comparison of 3.5 cm and transcorporal cuffs in high-risk artificial urinary sphincter populations

Michael T. Davenport, Abdulhadi M. Akhtar, Nabeel A. Shakir, Adam S. Baumgarten, Yooni A. Yi, Rachel L. Bergeson, Ellen E. Ward, Allen F. Morey

Carcinoembryonic antigen related cell adhesion molecule 6 promotes the proliferation and migration of renal cancer cells through the ERK/AKT signaling pathway

Rujian Zhu, Jiong Ge, Junjie Ma, Junhua Zheng

Original Article

Neurogenic bladder: management of the severely impaired patient with complete urethral destruction: ileovesicostomy, suprapubic tube drainage or urinary diversion—is one treatment modality better than another?

Douglas A. Husmann, Boyd R. Viers

Surgical Technique

Robotic urethral reconstruction: redefining the paradigm of posterior urethroplasty

Timothy C. Boswell, Kevin J. Hebert, Matthew K. Tollefson, Boyd R. Viers

Case Report

Microscopic testicular sperm extraction or post-operative sperm reversal in functional Leydig cell tumor: case report

Zhongyan Liang, Zhanwang He, Chong Chen, Fengbin Zhang, Jingping Li, Jinggen Wu

Ewing’s sarcoma/primitive neuroectodermal tumor of the kidney: a case report and literature review

Shasha Zhang, Yaying Li, Rongpin Wang, Bin Song

Editorial Commentary

Are we really seeking for equivalence?—The virtue of the robot is in technology

Aldo Brassetti, Riccardo Mastroianni, Giuseppe Simone

A multi-omics approach to understanding the field effect in bladder cancer

Xue Li, Ali Hashemi Gheinani, Rosalyn M. Adam

Urinary tract infection after radical cystectomy: a vexing problem despite prophylactic antibiotics

Joseph Y. Clark, Jay D. Raman

The challenge of matching assays to biology in DNA damage response biomarkers for response to radiotherapy in bladder cancer

Neil B. Desai, Aditya Bagrodia

Predicting perioperative mortality after radical cystectomy: comorbidity assessment tools are only part of the puzzle

Valérie Fonteyne, Elke Rammant, Karel Decaestecker

CD47 targeted near-infrared photo-immunotherapy: a promising tool combining monoclonal antibodies and photodynamics for treating human bladder cancer

George Bou Kheir, Fouad Aoun, Thierry Roumeguere

Dosimetric and clinical factors predicting quality of life after post prostatectomy radiation therapy: useful tool or not?

Christian Carrie, Gabriel Bringeon

Focused Issue on Management of Non-muscle Invasive Bladder Cancer

Focused Issue: Detection of Lymph Node Metastases in Genitourinary Cancers edited by Dr. Baris Turkbey

Translational Andrology and Urology is indexed in SCIE: A milestone for the development of TAU

Welcome to the Visualized Minimally Invasive Urological Surgery Column, a section featured by high-quality surgical videos!

TAU Annual Report (2018)

Focused Issue: Personalized Prostate Cancer Care edited by Drs. Soroush Rais-Bahrami and Jennifer B. Gordetsky

Focused Issue: Male Genitourinary Reconstruction and Trauma edited by Drs. Benjamin N. Breyer and E. Charles Osterberg

Focused Issue: Knowledge Gaps in Male Infertility edited by Drs. James M. Hotaling and Ranjith Ramasamy

Focused Issue: Radiation Therapy for Prostate Cancer edited by Dr. Mark K. Buyyounouski

Focused Issue: Active Surveillance for Prostate Cancer edited by Drs. Marc A. Dall’Era, Benjamin J. Davies, Scott Eggener

Focused Issue: Prostate Cancer Screening and Active Surveillance in the Western World edited by Dr. Monique J. Roobol

Focused Issue: Bladder Cancer: Genetics and Biomarker for Optimized Clinical Decision-making and Improved Outcomes by Dr. Michael Rink

Focused Issue: Penile Prosthesis and Penile Implants by Dr. Jason R. Kovac

Focused Issue: Management of Penile Cancer

Focused Issue: Sperm DNA Fragmentation by Drs. Ashok Agarwal, Ahmad Majzoub, Sandro C. Esteves and Chak-Lam Cho

Focused Issue: Technique and Complications from the Masters in Andrologic Surgery edited by Dr. Tobias S Kohler

Focused Issue: Functional Urology by Dr. Johan Gani and Helen E. O’Connell

Focused Issue: Magnetic Resonance Imaging in Prostate Cancer by Drs. Marc A. Bjurlin, Andrew B. Rosenkrantz, Herbert Lepor and Samir S. Taneja

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