Background: As the development of laparoscopic instruments
and techniques, many various laparoendoscopic single-site
(LESS) surgery have been performed worldwidely.
Objective: To introduce a new homemade single-port device
to perform LESS simple nephrectomy (LESS-SN) and show
the comparative study with standard laparoscopic simple
Methods: We carried out a retrospective study comparing 8
LESS-SN with 13 SL-SN that were performed between March
2007 and August 2011 by a single surgeon. The indications
included nonfunctioning kidney and renal tuberculosis. Apart
from homemade single-port devices, no special LESS surgical
instruments were used. Demographics and clinical outcomes
were collected and compared. Additionally, we obtained data on
medial cost, first time to flatus and first time to defecation.
Results: All cases were completed eventfully, except that
1 case in SL-SN group needed conversion to open surgery
for diaphragmatic injury and hemarrhea. The demographic
data of the 2 groups had no significant differences. The mean
operative time of two groups were 116.12±39.64 min and
138.07±48.62 min, respectively (P=0.30). Both postoperative
stay and gastrointestinal function recovery were similar. Beyond
cosmetic advantage, LESS-SN may reduce the blood loss
during operation. The postoperative hemoglobin (137.75 vs.
115.70 g/dL) in LESS-SN was statistical more than the SL-SN
group (P=0.02). The complication rates were 25% and 23.1%,
repectively (P=1.00). stress ulcer (n=1) and hypoproteinemia
(n=1) in LESS-SN and pyrexia (n=1), diaphragmatic injury and
hemarrhea (n=1), blood loss anemia (n=1) in SL-SN occurred.
Conclusions: Although the operations of LESS-SN were much
more difficult, the perioperative outcomes were comparable with
standard procedures. The LESS simple nephrectomy with new
homemade single-port devices were safe and cost-effective.