Health-related quality of life in bladder cancer patients undergoing radical cystectomy and urinary stoma: still many gaps
Health-related quality of life (HRQoL), defined by the World Health Organization as “Individuals’ perceptions of their position in life in the context of the culture and value systems in which they live and in relation to their goals, expectations, standards, and concerns”, has recently gained increasing interest in the field of uro-oncology and is considered a relevant treatment-related outcome together with survival (1,2). It represents a dynamic, highly subjective, theoretical construct with multiple domains that can be influenced by cultural, demographic, and social variables. Radical cystectomy (RC) is one of the most traumatic cancer operations in terms of HRQoL impairment and the impact of the type of urinary diversion on this outcome has become the subject of intense debate in recent years (3,4). Orthotopic neobladder reconstruction, which is the preferred method for urinary diversion in suitable patients, may provide potential advantages in terms of HRQoL (5).