It is high time for clinical application of sperm DNA fragmentation testing

Chak-Lam Cho, Ashok Agarwal, Ahmad Majzoub, Sandro C. Esteves


We read with interest the commentary by Drs. Basar and Kahraman (1). The authors provide a comprehensive review of sperm DNA fragmentation (SDF) from etiologies and assisted reproduction outcomes to treatment strategies. We wish to further elaborate the discussion on the use of SDF testing in managing varicocele.