AB200. Treatment effect of TURP plus urethral sphincter botox A injection on male neurogenic micturition dysfunction

Objective: To investigate the treatment effect of TURP plus urethral sphincter botox A injection on male neurogenic micturition dysfunction.

Methods: Sixteen cases of male neurogenic bladder dysfunction patients. Age from 50 to 68 years old. Average 56 years old. All patients have dysuria symptom with normal bladder capacity. Detrusor underactivity 15 cases. Normal detrusor contractility 1 case. Reasons for neurogenic bladder: spinal cord injury 8 cases, spinal cord tumor 3 cases, postencephalitic 1 case, unknown reasons 4 cases, re-injection 1 case. Residual urine from 80 to 220 mL. Different degrees of prostatic hyperplasia were verified by ultrasound in 15 cases. Routine TURP were administrated under plasma cystoscopy. 100u botox A was injected into urethral sphincter muscle in 10 spots evenly. Symptom scores and ultrasound residual urine were recorded before and 4 weeks after surgery. Results were analyzed for treatment effect estimation.

Results: The average residual urine volume reduced from 154.8sidua to 57.3erage mL (P<0.01). Three cases stress urinary incontinence were observed, and reduced or recovered after 2–3 months pelvic floor muscle training. All patients were satisfied with the treatment results. The treatment effect lasted more than 15 months.

Conclusions: TURP plus urethral sphincter botox A injection is an effective and economic treatment on male neurogenic micturition dysfunction.

Keywords: TURP; botox A; neurogenic bladder; micturition dysfunction