TY - JOUR AU - Regauer, Sigrid PY - 2016 TI - Mast cell activation syndrome in pain syndromes bladder pain syndrome/interstitial cystitis and vulvodynia JF - Translational Andrology and Urology; Vol 5, No 3 (June 01, 2016): Translational Andrology and Urology (Peyronie’s Disease) Y2 - 2016 KW - N2 - In the short article by Prof. Ratner on mast cell activation syndrome and its overlooked or dismissed possible contribution to bladder pain syndrome/interstitial cystitis (BPS/IC) (1), the author outlines that increased numbers of activated mast cells (mast cell activation syndrome) may play a role in the development of painful BPS/IC. This association has been long recognized by the European Society for the Study of Interstitial Cystitis (ESSIC) which proposes mast cell counts in the detrusor muscle with a density >28 mast cells/mm 2 as diagnostic criterion for BPS/IC (2). UR - https://tau.amegroups.org/article/view/9828