TY - JOUR AU - DiGiorgio, Lorenzo AU - Sadeghi-Nejad, Hossein PY - 2016 TI - Off label therapies for testosterone replacement JF - Translational Andrology and Urology; Vol 5, No 6 (December 18, 2016): Translational Andrology and Urology (Testosterone Replacement Therapy) Y2 - 2016 KW - N2 - The incidence of hypogonadism has been steadily increasing over the last few years. Exogenous testosterone has been the standard treatment for hypogonadal men, but is associated with suppression of spermatogenesis as well as other possible adverse effects. There are other medications, currently considered “off label” for androgen replenishment, that exert their effect through modulation of the hypothalamic-gonadal axis. These medications increase endogenous testosterone levels and offer a different therapeutic approach. This review will focus on these alternative (off-label) therapies for androgen replacement in men. UR - https://tau.amegroups.org/article/view/11490