The role of sperm DNA testing on male infertility

Ateş Kadioglu, Mazhar Ortac


Male factor is responsible for nearly 50% of all causes of infertility. Approximately 30–40% of the cases are deemed idiopathic, as there are no identifiable factors to explain the abnormal semen analysis results. Semen analysis (sperm concentration, motility and morphology) is still used for routine male infertility assessment; however, these parameters have shown to be limited as surrogate markers of male fertility. In fact, nearly 15% of patients who are suffering from male infertility have a normal semen analysis.