Vitaly Margulis, MD

Department of Urology, The University of Texas Southwestern Medical Center, Dallas, TX, USA

Upon completion of rigorous clinical training in urology, Dr. Margulis entered into urologic oncology fellowship at the MD Anderson Cancer Center, under mentorship of Dr. Christopher G. Wood. His choice of fellowship training was based primarily on the institution’s commitment to providing basic academic, technical and judgmental skills, and a framework necessary for conducting effective cancer management, research, and teaching. Dr. Margulis’s research focus, during the two years of dedicated basic science training, was on understanding the molecular biology of renal cell carcinogenesis and progression as a model for developing novel diagnostic and therapeutic strategies for this disease. Specifically, his group investigated the role of TGF-beta signal transduction in human renal cell carcinoma with goals of developing targeted therapies. This project was federally funded through an R01 mechanism (R01 CA104505-01 “TGFbeta Receptor Biology in Human Renal Cell Carcinoma”).

 Currently, Dr. Margulis is Associate Professor of Department of Urology, The University of Texas Southwestern Medical Center. He supervises a fully equipped and staffed basic science laboratory with a three year institutional start-up fund commitment and a 50% protected research time allocation. He has also established a close working relationship with basic/translational scientists at The University of Texas Southwestern Medical Center in the department of Urology, Pathology and Medical Oncology. Dr. Margulis’s research interests include metastatic progression and resistance to targeted therapies and olecular biology involved in renal cell cancer tumorigenesis.