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Persistent, long-term risk for ureteroenteric anastomotic stricture formation: the case for long term follow-up

  
@article{TAU29662,
	author = {David Y. Yang and Stephen A. Boorjian and Mary Beth Westerman and Robert F. Tarrell and Prabin Thapa and Boyd R. Viers},
	title = {Persistent, long-term risk for ureteroenteric anastomotic stricture formation: the case for long term follow-up},
	journal = {Translational Andrology and Urology},
	volume = {0},
	number = {0},
	year = {2019},
	keywords = {},
	abstract = {Background: Up to one in ten patients undergoing cystectomy with urinary diversion develop a ureteroenteric stricture (UES). Despite unrecognized ureteral obstruction contributing to infection, nephrolithiasis, and/or progression of kidney disease, the long-term natural history and risk factors associated with UES remains understudied. Herein, we report our single institutional experience with the long-term incidence, clinical presentation, and risk factors associated with UES formation following urinary diversion. 
Methods: We reviewed 2,285 patients who underwent RC with urinary diversion between 1980–2008. UES was defined as radiographic evidence of ureteral obstruction at the level of the ureteroenteric anastomosis. The diagnosis of benign UES was confirmed by pathology. UES-free survival was estimated using the Kaplan-Meier method. The association between clinicopathologic features and the development of a UES were assessed using multivariable models.
Results: A total of 192 (8%) patients developed a benign UES, at a median of 7 months (IQR 4–24) following RC, with 5% occurring after 10 years. Seventy seven percent of patients exhibited signs and/or symptoms of ureteral obstruction. Patients who developed a UES had a greater body mass index (BMI) (28 vs. 27), operative time (330 vs. 301 minutes) and were more likely to experience a },
	issn = {2223-4691},	url = {http://tau.amegroups.com/article/view/29662}
}