TY - JOUR AU - Maas, Moritz AU - Stenzl, Arnulf PY - 2019 TI - Should every patient with muscle-invasive bladder cancer receive neoadjuvant chemotherapy? JF - Translational Andrology and Urology; Vol 8, Supplement 3 (July 16, 2019): Translational Andrology and Urology Y2 - 2019 KW - N2 - The use of cisplatin-based neoadjuvant chemotherapy (NAC) for all patients with muscle-invasive bladder cancer (MIBC) is recommended by current guidelines (1,2). However, the study of Bhindi et al . suggest, that patients not responding to NAC show an inferior survival than a comparable control group (3). Furthermore, only 20–38% of the patients exposed towards NAC show a histopathological response (4). Taking these aspects and the known chemotherapy-related toxicity into consideration leads both, providers and patients, to the question whether the potential benefits of NAC outweigh its disadvantages. UR - https://tau.amegroups.org/article/view/24487