TY - JOUR AU - Czarniecki, Marcin AU - Mena, Esther AU - Lindenberg, Liza AU - Cacko, Marek AU - Harmon, Stephanie AU - Radtke, Jan Philipp AU - Giesel, Frederick AU - Turkbey, Baris AU - Choyke, Peter L. PY - 2018 TI - Keeping up with the prostate-specific membrane antigens (PSMAs): an introduction to a new class of positron emission tomography (PET) imaging agents JF - Translational Andrology and Urology; Vol 7, No 5 (October 22, 2018): Translational Andrology and Urology (Detection of Lymph Node Metastases in Genitourinary Cancers) Y2 - 2018 KW - N2 - Prostate-specific membrane antigen (PSMA) targeted positron emission tomography (PET) is an emerging prostate cancer imaging method, which has been reported to have a higher sensitivity and specificity than the currently approved PET imaging agents. Multiple PSMA ligands are being investigated around the world and applications range from primary tumor characterization, to local staging, biochemical recurrence, metastasis, and image-guided interventions. The most investigated PET tracers are labelled with 68-Gallium or 18-Fluoride and are discussed in this review. Additionally, 99mTc labeled PSMA agents for single photon emission computed tomography (SPECT) imaging are elucidated as an alternative method of PSMA image acquisition. UR - https://tau.amegroups.org/article/view/21120