TY - JOUR AU - Jue,, Joshua S. AU - Ramasamy, Ranjith PY - 2017 TI - Significance of positive semen culture in relation to male infertility and the assisted reproductive technology process JF - Translational Andrology and Urology; Vol 6, No 5 (October 26, 2017): Translational Andrology and Urology (Management of Penile Cancer) Y2 - 2017 KW - N2 - There are currently no WHO guidelines on the indications for semen culture; however, semen cultures are performed in the evaluation of male infertility and the assisted reproductive technology (ART) process. The relevance and significance of positive semen cultures is widely debated in the literature, with no current consensus on the usefulness of this test in relation to male infertility. We review the pathogenic mechanisms of potentially pathogenic bacteria, general bacteria, urethral flora, and skin flora on sperm parameters. We also present, possible routes of semen contamination, measures to reduce contamination, and the clinical significance of culture contamination. First, it is critical to distinguish round cells in semen as leukocytes from immature germ cells. Second, it is critical to distinguish leukocytospermia from infected semen in order to guide management. UR - https://tau.amegroups.org/article/view/16899