AB047. Clinic therapeutic effect of sigmoid orthotopic neobladder after radical cystectomy

Objective: To investigate the clinic therapeutic effect of sigmoid orthotopic neobladder after radical cystectomy.

Methods: Sixteen patients with invasive bladder cancer (all males; age range from 53 to 75 years) were admitted and underwent radical cystectomy and sigmoid orthotopic neobladder.

Results: The 16 patients were hospitalized for 37 to 62 d, with an average of 51 d. All the 16 patients were followed up for a mean of 26 months (range from 5 months to 6 years). The serum creatinine and blood urea nitrogen levels were both in the normal range without acidosis in all the cases. No cases had unilateral ureteral urine reflux during cystography. Of the 16 patients 14 cases (87.5%) achieved continence during daytime; 6 cases (37.5%) were incontinent at night, but all of them could control urination by being woken up at night. The capacity of the neobladder was 245 to 380 mL with an average of 316 mL and the maximal pressure of the neobladder during filling was 28 to 57 cmH₂O (1 cmH₂O =0.098 kPa) with an average of 39 cmH₂O.

Conclusions: As an operation the sigmoid orthotopic neobladder can be performed easily without serious postoperative complications and more reliable results. This operation may be generally applied in clinical practice.

Keywords: Bladder neoplasms; radical cystectomy; sigmoid orthotopic neobladder