Introduction and Objective: Prophylactic oral antibiotics
prior to transrectal prostate biopsy are administered to reduce
complications of urinary tract infections. In this study, we
investigated whether prophylactic oral antibiotics administered
on a day before the biopsy can reduce the complications of
transrectal prostate biopsy.
Methods: Between Januar y 2010 and June 2011, we
retrospectively analyzed the medical records of 209 patients who
underwent urine culture after transrectal prostate biopsy. We
divided the subjects into two groups (group 1:155 patients who
were administered prophylactic oral antibiotics on a day before
the biopsy, group 2:54 patients who took prophylactic oral
antibiotics on the day of the biopsy). We performed povidone
enema to all patients on the day of the biopsy. Age, presence of
diabetes, prostate size, presence of infectious complications and
other complications were documented.
Results: There were no significant differences in age, presence of diabetes, and prostate size (66.4 years vs. 66.0 years, P=0.744;
10 vs. 8, P=0.060; 44.7 mL vs. 44.5 mL, P=0.341). The incidence
of overall complications was 9.6% (n=20). The incidence of
urinary tract infections between the two groups did not differ
significantly (10 vs. 5, P=0.530). Other complications were
noted such as persistent gross hematuria (2 patients) and
acute urinary retention (3 patients). However, there were no
significant differences between the two groups (1 vs. 1, P=0.158;
2 vs. 1, P=0.319).
Conclusions: Prophylactic oral antibiotics administered on
a day before the transrectal prostate biopsy can not reduce
infectious complications that occurred after biopsy.