Objective: To evaluate the impact of reservation of nervesparing
laparoscopic radical prostatectomy (NSLRP) on the
postoperative quality of life.
Methods: Laparoscopic radical prostatectomy was applied
in 245 patients with localized prostate cancer (Pca) between
February 2001 and July 2007. Of them, 56 patients with
preoperative erectile function (IIEF5 scores ranged from 16
to 24) and indications (PSA <10 ng/mL; Gleason scores <7;
Age <70 years old) underwent NSLRP. Among them, 39 cases
had bilateral NSLRP, and 17 cases received unilateral NSLRP.
After surgery, continually low-dose PDE5 inhibitor therapy,
intracavernous injection, or vacuum constriction devices were
performed for 3 months to restore the function of penis at the
early stage. The patients' erectile function and urinary control
were evaluated one year after the surgery.
Results: About 69% patients who had undergone NSLRP P
preserved sexual function one year after the surgery, among
which 28 patients (50%) regained the intercourse ability with
the assist of PDE5 inhibitor. The IIEF5 scores ranged 0-7 in 11
cases (20%), 8-11 in 18 cases (32%), 13-21 in 23 cases (41%),
and 22-25 in 4 cases (7%). Urinary control rate at 6 and 12
months after the surgery were 92% and 99.5%, respectively.
Conclusions: The NSLRP can effectively preserve most of
the patients' sexual function and enhance the early recovery
of erectile function and urinary continence. Low-dose PDE5
inhibitor after NSLRP can benefit the early recovery of erectile