Objective: To explore the correlation between seminal elastase
and seminal parameters in infertile men.
Methods: Semen samples were harvested from 616 infertile men
who were treated in our center from January 2009 to March 2011.
The elastase was graded as follows: normal, <290 ng/mL; probable
positive, 290-1000 ng/mL; and positive, ≥1000 ng/mL. Seminal
parameters between samples with different levels of elastase were
Results: Seminal leucocytes and pH was significantly elevated
as elastase increased (P<0.05), showing a positive correlation
between them; on the contrary, sperm concentration, percentage
of rapid progressive motility sperm, sperm viability, curvilinear
velocity, and straight line velocity were decreased (all P<0.05).
Age, semen volume, and percentage of immotile sperm or normal
sperm morphology showed no significant relationship with the
elastase levels (all P>0.05).
Conclusions: Seminal elastase is associated with the seminal
parameters in fertile man, and therefore may be used as an
indicator of genital infections.