Background: Little is known about young ketamine abusers
presented with lower urinary tract symptoms.
Objective: To discuss the method of treatment of bladder
contracture caused by abusing Ketamine.
Design, Setting and Participants: Between November
2006 and February 2009, 25 patients with lower urinary tract
symptoms (LUTS) for abusing ketamine were treated with
augmentation cystoplasty in our hospital, and patient data were
Intervention: We obtained a detailed history and physical
examination along with cystoscopy, urine culture, urinalysis, and
urine cytology in all patients. All patients underwent bladder
biopsy, which were all reviewed by a single pathologist. IVP and
other ancillary tests were obtained as indicated. All patients were
required to withdraw the narcotics and the experimental medine
were given, all symptoms without obvious alleviated, we use
Sigmoidcystoplasty to treat them.
Measurements: We use Sigmoidcystoplasty to treat them,
urination easy and smooth.
Results and Limitations: Sigmoidcystoplasty is effective, follow up from 6 months to 24 months, Urodynamics significant
improvement. A marked increase in the Qmax, residual urine
significantly reduced. No complainted urinary incontinence, no
enuresis, frequency, urgency. Urine routine is no abnormality
seen. Cystography could not find ureter reflux, bladder capacity
is larger than before. B ultrasound examinetion of 23 cases
demonstrated the disappearance of bilateral hydronephrosis or
Conclusions: Sigmoidcystoplasty could enlarge bladder
capacity and compliance, ameliorate bilateral hydronephrosis
and the lower urinary system dysfunction, and improve the
patients quality of life.