This issue of Translational Andrology and Urology (TAU) is devoted to “Detection of Lymph Node Metastases in Genitourinary Cancers”, which is an evolving topic due to continuous high-level research in the field specifically in imaging and imaging guided surgery/intervention. In this issue, many experts shared their clinical and research experiences through high quality review articles on a diverse group of genitourinary cancers and they present a wide variety of lymph node detection techniques including conventional imaging, sentinel node imaging, novel positron emission tomography and magnetic resonance imaging. As the guest editor of TAU, I aimed to include the most up-to date information on the topic. I would like to gratefully acknowledge the time and dedication of all participating authors, as well as the diligent support and assistance of the Science Editor, Mira Wu. I hope that our readers will be well-rewarded for investing time in reading the comprehensive materials presented in this issue of TAU and innovative ideas will be initiated based on these reads.