The price and value of sperm DNA fragmentation tests

Ashok Agarwal, Chak-Lam Cho, Sandro C. Esteves, Ahmad Majzoub


Drs. Fraczek and Kurpisz, in their insightful commentary, highlighted the pitfalls of the current sperm DNA fragmentation (SDF) testing (1). These authors remarked that the association between SDF and clinical outcome of assisted reproduction is not without controversy in the literature. An interesting study cited by these authors proposes the predictive values of sperm vitality on SDF (2) and deserves further discussion in our response.