Despite limitations, sperm DNA fragmentation testing provides unique information complementary to but distinct from semen analysis results

Sandro C. Esteves, Ahmad Majzoub, Ashok Agarwal


Drs. Tadros and Sabanegh highlighted three critical aspects regarding the clinical utility of sperm DNA fragmentation (SDF) testing in their commentary (1) concerning the recently published practice recommendations for SDF testing based on clinical scenarios by Agarwal et al. (2).