Unraveling the utility and limitations of clinical practice guidelines

Sandro C. Esteves, Ashok Agarwal, Ahmad Majzoub

Abstract

Dr. Glina in his commentary (1) responding to the practice recommendations for sperm DNA fragmentation (SDF) testing based on clinical scenarios by Agarwal et al. (2) discussed the challenges of elaborating male infertility guidelines and the limitations of SDF methods.