Article Abstract

Trimodality therapy in variant urothelial carcinoma: choose wisely

Authors: Panagiotis J. Vlachostergios, Christopher Jakubowski, Scott T. Tagawa


Trimodality bladder-sparing therapy with maximal transurethral resection (TUR) followed by combined chemoradiation is an alternative to neoadjuvant chemotherapy followed by radical cystectomy (RC) in optimally selected patients treated in expert multidisciplinary centers. Little has been studied regarding the impact of variant urothelial histology when utilizing a trimodality therapy (TMT) approach. Investigators from Boston, Massachusetts retrospectively reviewed their long-term experience with this approach.