Article Abstract

Measure of sperm DNA fragmentation (SDF): how, why and when?

Authors: Amir Amiri-Yekta, Christophe Arnoult, Pierre F. Ray


Sperm DNA fragmentation (SDF) is a frequent topic of discussion in the field of reproductive technologies and three main questions remain unanswered: (I) which of the many assays available is the “best” test to measure SDF? (II) can a measure of SDF be useful for patient’s diagnosis, prognosis and permit to adopt the best therapy for the patient? and (III) if deemed relevant, for which indication a measure of SDF should be encouraged?