Conversations in the operating room: history of the development of a promising new compound for the treatment of premature ejaculation

Despite its large prevalence (2,3) Premature Ejaculation (PE) remains incompletely understood; consequently, its treatment is diverse and frequently non-specific (4). Over the years, many sundry approaches have been used. In the days of Freudian theory, PE was thought to result from unresolved narcissism or an unconscious, deep-seated hatred of women (5) PE has long been considered a learned behavior with a significant psychological component, thus psychosexual therapies that combine behavioral interventions and counseling to lessen performance anxiety remain widely used, despite limited and temporary success.